Found 10 matching trials
Phase I Study to Assess the Effect of Food on AZD1775 Pharmacokinetics in Patients With Advanced Solid Tumours PHASE1 The purpose of this study is to assess the effect of food on the pharmacoki...
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AZD1775 Continued Access Study to Assess Safety and Tolerability for Patients Enrolled in AZD1775 Clinical Pharmacology Studies PHASE1 Open-label, non-randomised study to provide continued access to AZD1775 for...
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Wee1 Kinase Inhibitor AZD1775 and Combination Chemotherapy in Treating Children, Adolescents and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia PHASE1 This phase I trial studies the side effects and best dose of wee1 kinase in...
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Multiple Locations
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Testing AZD1775 inC Combination With Radiotherapy and Chemotherapy in Cervical, Upper Vaginal and Uterine Cancers PHASE1 This phase I trial studies the side effects and best dose of adavosertib wh...
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University of California Davis Comprehensive Cancer Center
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CISPLATIN + AZD-1775 In Breast Cancer PHASE2 This research study is studying a combination of drugs as a possible treatm...
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Dana-Farber Cancer Institute
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Cisplatin With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent or Metastatic Head and Neck Cancer PHASE2 This randomized phase II trial studies how well cisplatin with or without W...
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Juravinski Cancer Centre at Hamilton Health Sciences
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Ph II Trial of Carboplatin and Pemetrexed With or Without AZD1775 for Untreated Lung Cancer PHASE2 The aim of this study is to combine AZD1775 with standard front-line chemot...
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Effects of AZD1775 on the PK Substrates for CYP3A, CYP2C19, CYP1A2 and on QT Interval in Patients With Advanced Cancer PHASE1 The purpose of this study is to determine whether AZD1775 has any effect on...
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Phase Ib Study AZD1775 in Combination With Carboplatin and Paclitaxel in Adult Asian Patients With Solid Tumours PHASE1 This is a phase Ib, open-label, multicentre study of AZD1775 administered o...
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AZD1775 for Advanced Solid Tumors PHASE1 BACKGROUND:
* Wee1 is a tyrosine kinase involved in the phosphorylation an...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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